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1985年9月至1987年10月,对从湖南省西部慈利县自然感染者分离的间日疟原虫,连续蚊传5代的27例病例,以氯喹1.5g(基质)3d疗法治疗。治疗后,13例短潜伏期(平均17.2d)病例的复发率为100%,第2～4次的复发率依次为76.9、62.5和20.0%;14例长潜伏期(平均287.2d)的复发率66.7％,第2次的复发率为37.5%,未见第3次复发。这两类间日疟复发类型的差异,主要表现于第1潜隐期,即潜伏期短者第1潜隐期长(平均243.4d),而潜伏期长者则第1潜隐期短(平均55.3d)。
From September 1985 to October 1987, 27 cases of Plasmodium vivax isolated from natural infected persons in Cili County, western Hunan Province were continuously treated with 5-chloroquine (matrix) for 3 days. After treatment, the recurrence rate was 100% in 13 cases of short latency (average 17.2 days), followed by 76.9%, 62.5% and 20.0% in the second to fourth cycles respectively. The relapse rate of 14 cases with long latency (average 287.2 days) was 66.7 %, The second recurrence rate was 37.5%, no third recurrence. The differences in the types of P. malaria relapse between the two groups were mainly in the first latent period, ie, the first latent period with a shorter incubation period (mean 243.4d), while the shorter incubation period with the first latent period (average 55.3 d).