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目的探讨分析胃癌淋巴结转移枚数与术后放疗疗效及相应病理检查结果的相关性。方法 2006年5月至2008年5月收治的胃癌患者,均行胃癌根治性手术治疗,术后诊断为胃癌伴淋巴结转移的患者214例。所有组内淋巴结转移行D2或D3式清扫,且治疗前后均予以放射治疗。结果胃癌患者淋巴结转移枚数与性别、年龄等一般因素无关系,而与肿瘤大小、浸润深度及分期呈正相关。淋巴结转移1~5个、6~9个及>9个的胃癌患者,其术后及放疗后5年生存率分别为50%、30%和<10%,三者之间差异有统计学意义(P<0.05)。结论胃癌患者胃周阳性淋巴结转移数与预后有关,结合肿瘤大小及生长浸润方式可以简便而准确地判断胃癌术后患者的预后情况。
Objective To investigate the correlation between the number of lymph node metastasis and the postoperative radiotherapy efficacy and the corresponding pathological findings. Methods From May 2006 to May 2008, patients with gastric cancer were treated by radical operation of gastric cancer, and 214 cases were diagnosed as gastric cancer with lymph node metastasis after operation. All patients with lymph node metastasis D2 or D3 type of cleaning, and were treated before and after radiotherapy. Results The number of lymph node metastasis in gastric cancer patients was not related to the general factors such as gender and age, but positively correlated with tumor size, depth of invasion and staging. The 5-year survival rates of patients with lymph node metastasis of 1 to 5, 6 to 9 and> 9 were 50%, 30% and <10% respectively after operation and after radiotherapy, the difference was statistically significant (P <0.05). Conclusions The number of metastatic gastric lymph nodes in gastric cancer is related to prognosis. Combined with the size of tumor and infiltration of gastric cancer, the prognosis of gastric cancer patients can be easily and accurately determined.