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目的探讨超敏C反应蛋白在冠心病诊断中应用。方法 2009年1月—2011年1月门诊或住院的冠状动脉粥样硬化性心脏病患者262例,无症状型冠心病组142例,心绞痛型冠心病组85例,心肌梗死型冠心病组35例,正常人对照组100例进行hs-CRP及血脂(TC、TG、HDL-C、LDL-C)检测并比较。结果无症状型冠心病组、心绞痛型冠心病组、心肌梗死型冠心病组与正常人对照组Hs-CRP检测值比较P<0.01有显著差异性。无症状型冠心病组、心绞痛型冠心病组与心肌梗死型冠心病组Hs-CRP检测值比较P<0.05有明显差异性。无症状型冠心病组、心绞痛型冠心病组、心肌梗死型冠心病组、正常人对照组血脂检测值比较P>0.05无显著差异性。结论 Hs-CRP的测定能够较敏感地对冠心病患者进行危险性评估,在预测冠心病的严重程度及心血管意外事件方面有着重要价值。
Objective To investigate the application of high sensitivity C-reactive protein in the diagnosis of coronary heart disease. Methods From January 2009 to January 2011, 262 outpatients or hospitalized patients with coronary atherosclerotic heart disease, 142 patients with asymptomatic coronary heart disease, 85 patients with angina pectoris type coronary heart disease, 35 patients with myocardial infarction type coronary heart disease Cases, normal control group of 100 cases of hs-CRP and serum lipids (TC, TG, HDL-C, LDL-C) were detected and compared. Results There was a significant difference of Hs-CRP in asymptomatic coronary heart disease group, angina pectoris coronary heart disease group, myocardial infarction-type coronary heart disease group and normal control group, P <0.01. Hs-CRP levels in asymptomatic coronary heart disease group, angina pectoris coronary heart disease group and myocardial infarction coronary heart disease group were significantly different (P <0.05). Asymptomatic coronary heart disease group, angina pectoris type coronary heart disease group, myocardial infarction type coronary heart disease group, the normal control group serum lipid values ?? compared P> 0.05 no significant difference. Conclusion The determination of Hs-CRP can be more sensitive in patients with coronary heart disease risk assessment, in the prediction of the severity of coronary heart disease and cardiovascular accidents have an important value.