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目的:观察清热方联合蒙脱石散治疗复发性口腔溃疡的临床疗效。方法:收集本院口腔科门诊患者240例,将患者随机分为2组各120例。治疗组采用清热方联合蒙脱石散治疗;对照组口服盐酸左旋咪唑片、复合维生素B片、维生素C片治疗。2组均以治疗2周为1疗程,1疗程结束后比较2组患者的临床疗效,观察治疗前后口腔溃疡部位、面积、充血及疼痛程度的变化。结果:临床疗效总有效率治疗组为94.2%,对照组为74.2%,2组总有效率比较,差异有显著性意义(P<0.05)。治疗后,2组患者溃疡面积、充血评分及疼痛评分与同组治疗前比较,差异均有显著性意义(P<0.05)。治疗后2组溃疡面积比较,差异无显著性意义(P>0.05),但充血评分、疼痛评分分别比较,差异均有显著性意义(P<0.05)。结论:清热方联合蒙脱石散可缩小复发性口腔溃疡患者的溃疡面积,改善溃疡面的充血程度,缓解患者的疼痛。
Objective: To observe the clinical efficacy of Qingrefang combined with montmorillonite in the treatment of recurrent oral ulcer. Methods: Two hundred and forty cases of patients in our department were collected and randomly divided into two groups of 120 cases. The treatment group was treated with Qingre Fang combined with montmorillonite powder; the control group was treated with levamisole hydrochloride tablets, vitamin B complex tablets and vitamin C tablets. Two groups were treated for 2 weeks for a course of treatment, after a course of treatment, the clinical efficacy of two groups were compared to observe the changes of oral ulcer site, area, congestion and pain before and after treatment. Results: The total effective rate of clinical curative effect was 94.2% in the treatment group and 74.2% in the control group. The total effective rate in the two groups was significantly different (P <0.05). After treatment, the ulcer area, congestion score and pain score of the two groups were significantly different from those before treatment (P <0.05). After treatment, there was no significant difference in the ulcer area between the two groups (P> 0.05). However, there were significant differences in the congestion score and pain score between the two groups (P <0.05). Conclusion: Qingre Fang combined montmorillonite powder can reduce the ulcer area of patients with recurrent oral ulcer, ulcer surface to improve the degree of congestion, relieve pain in patients.