复发性肝癌再切除的探讨

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目的:探讨肝癌术后复发再切除的临床价值和手术指征以及再切除方式。方法:我院自1988年至1998年对原发性肝癌施行切除术233例 ,有20例术后复发获再切除共26例次。其中伴肝硬化16例 ,占80 % ;肿瘤<5cm19例次 ,>5cm7例次 ;行肝叶切除3例 ;肝段切除7例次 ;局部切除12例次 ;肝部分切除3例次 ;右后叶切除1例。结果:无1例死亡,再切除后1~5年生存率为95 %、65 %、35 %、30 %、30 %。有1例经4次再切除已生存10年。结论:1)肝癌术后定期AFP和B超复查有助于早期发现复发。2)复发性肝癌再切除可明显提高生存率。3)复发性肝癌只要肝功能ChildA级 ,病灶局限 ,不侵犯肝门血管 ,余肝有明显代偿性增生 ,应争取再切除。4)复发性肝癌再切除的方式以局部切除或肝段切除较安全 ,尽量不做肝叶或半肝切除。 Objective: To explore the clinical value, surgical indications, and re-excision methods of re-excision of liver cancer after recurrence. METHODS: In our hospital, 233 cases of primary liver cancer were removed from 1988 to 1998, and 20 cases of recurrence were re-excised in 26 cases. There were 16 cases with liver cirrhosis, accounting for 80%; tumors <5cm19 cases,> 5cm7 cases; 3 cases of liver lobectomy; 7 cases of hepatectomy; 12 cases of local resection; 3 cases of hepatectomy; Posterior lobectomy in 1 case. RESULTS: None of the patients died. The 1- to 5-year survival rate after re-excision was 95%, 65%, 35%, 30%, and 30%. One case has survived 4 re-excisions for 10 years. Conclusions: 1) Regular AFP and B-ultrasound after liver cancer surgery can help early detection of recurrence. 2) The re-excision of recurrent liver cancer can significantly improve the survival rate. 3) Recurrence of liver cancer as long as the liver function ChildA grade, lesions are limited, does not invade the hepatic portal vein, the liver has obvious compensatory hyperplasia, should strive for re-excision. 4) Resection of recurrent hepatocellular carcinoma is safer with local resection or hepatectomy. Hepatectomy or hepatectomy should be avoided.
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