本文比较了用近交系与非近交系小鼠测定造血干细胞的结果。测定内源性或外源性脾结节时,用近交系小鼠可获得照射剂量或注入的骨髓有核细胞数与脾结节生成数之间的线性关系。而用非近交系小鼠,则缺乏线性关系。用体内扩散盒琼脂培养法测定柱系定向干细胞(CFU-C)时,用两种小鼠皆可获得种入的细胞数与细胞团生成数之间的线性关系。 This article compared the results of hematopoietic stem cells in inbred and non-inbred mice. When measuring endogenous or exogenous splenic nodules, a linear relationship between the irradiation dose or the number of injected bone marrow nucleated cells and the number of spleen nodules was obtained using inbred mice. With non-inbred mice, there is a lack of linearity. When column-oriented stem cells (CFU-C) were assayed using the in vivo diffusion agar agar culture method, a linear relationship between the number of seeded cells and the number of cell clusters was obtained in both mice.