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输血后肝炎有三分之一为非甲非乙型肝炎,作者用干扰素治疗11例输血后发生肝功能异常的患者,并检测血清转氨酶和肝活检观察疗效。 11例输血后发生肝功能异常的患者中,5例为输血后慢性非甲非乙型肝炎(男4例,女1例,年龄42～60岁),6例为输血后急性非甲非乙型肝炎(男2例、女4例,年龄19～54岁),潜伏期急性肝炎为15～92天,慢性肝炎为30～90天。慢性肝炎血清转氨酶升高12个月以上(12～30个月),其值在正常值上限2倍以上超过6个月。所有患者血清IgM抗-HA、HBsAg、抗核抗体、线粒体抗体、平滑肌抗体和类风湿因子均阴性。治疗前进行肝活检
One-third of post-transfusion hepatitis was non-A, non-B hepatitis. The authors used interferon to treat 11 patients with abnormal liver function after transfusion and tested the efficacy of serum transaminase and liver biopsy. Among the 11 patients with abnormal liver function after transfusion, 5 were non-A non-B hepatitis after transfusion (4 males and 1 female, aged 42-60 years), and 6 were non-A non-B Hepatitis (2 males, 4 females, aged 19-54 years), acute hepatitis for 15 to 92 days, and chronic hepatitis for 30 to 90 days. Chronic hepatitis serum transaminase increased more than 12 months (12 to 30 months), its value in the upper limit of 2 times more than 6 months. All patients’ serum IgM anti-HA, HBsAg, antinuclear antibody, mitochondrial antibody, smooth muscle antibody and rheumatoid factor were negative. Liver biopsy before treatment