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在研究盾壳霉（Ｃｏｎｉｏｔｈｙｒｉｕｍｍｉｎｉｔａｎｓ）生态特性中，我们首次发现了该菌可产生抗细菌物质。本试验测定了盾壳霉产生的抗细菌物质对１３种（或类型）细菌的抑制作用。并对该物质的热稳定性、酸碱稳定性、纸层析和纸电泳迁移作了研究。结果表明：该物质可抑制多种革兰氏阴性和阳性细菌，尤其对水稻白叶枯病菌（Ｘａｎｔｈｏｍｏｎａｓｏｒｙｚａｅｐｖ．ｏｒｙｚａｅ）的抑制作用最好；可耐１２１℃１ｈ高温处理；在酸性条件下稳定，在ｐＨ值大于或等于１１的碱性溶液中丧失活性；纸层析和纸电泳分析表明该物质含有２种有效成份，皆为非水溶性物质，其中一种是中性化合物，另一种是弱酸性化合物。
In studying the ecological properties of Coniothyrium minitans, we first found out that the bacteria can produce antibacterial substances. This test determined the inhibitory effect of anti-bacterial substances produced by C. conidia on 13 species (or types) of bacteria. The thermal stability, acid-base stability, paper chromatography and paper electrophoresis migration of the material were studied. The results showed that this material can inhibit a variety of Gram-negative and positive bacteria, especially for Xanthomonas oryzaev.oryzae. It has the highest inhibitory effect at 121 ℃ for 1h, is stable under acidic conditions, alkaline solution with pH value greater than or equal to 11 lost activity; paper chromatography and paper electrophoresis analysis showed that the substance contains two active ingredients, all of which are water-insoluble substances, one of them is a neutral compound and the other is weak Acidic compounds.