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肌上皮肿瘤的免疫组化标记物包括S-100,Myos-in,GFAP,Desmin和Keratin.但是,没有一种标记物能确定肌上皮来源.已证实肌动蛋白(Action)存在于正常涎腺的肌上皮细胞中,肌动蛋白在肌上皮肿瘤细胞中的表达已成为一个诊断标准。然而,本实验发现波形蛋白(Vimentin)是肌上皮肿瘤分化的最早的指标之一. 材料和方法 24例已明确诊断的涎腺肿瘤标本,其中2例基底细胞腺瘤,7例多形性腺瘤,2例肌上皮瘤,7例腺样囊性癌(2例管状,4例筛状,1例突性)和6
Immunohistochemical markers of myoepithelial neoplasia include S-100, Myos-in, GFAP, Desmin, and Keratin However, none of the markers identify myoepithelial origin. It has been demonstrated that act exists in normal salivary glands Of myoepithelial cells, the expression of actin in myoepithelial tumor cells has become a diagnostic criterion. However, we found that Vimentin is one of the earliest markers of myoepithelial neoplasia.Materials and Methods 24 cases of salivary gland tumor have been diagnosed, including 2 basal cell adenoma, 7 pleomorphic adenoma , 2 cases of myoepithelioma, 7 cases of adenoid cystic carcinoma (2 cases of tubular, 4 cases of sieve, 1 cases of sudden) and 6