论文部分内容阅读
本文研究了顶体蛋白酶抑制剂KF-950对人精子功能的影响。结果表明:KF-950对人精子的作用与其浓度和作用时间有关。经≥0.21ml KF-950处理,随着时间的延长,精子活率和活力明显下降;精子膜功能有不同程度的损害,且对精子头部膜的损害较其对尾部膜的损害严重,顶体脱落率及已发生顶体反应的精子死亡率明显上升。KF-950可通过破坏精子膜而影响精子的功能。
This article studies the effect of the acrosin protease inhibitor KF-950 on human sperm function. The results showed that the effect of KF-950 on human sperm was related to its concentration and action time. After treated with ≥0.21 ml KF-950, the sperm motility and vitality decreased significantly with time, the function of sperm membrane damaged in different degrees, and the damage to the sperm head membrane was more serious than the damage to the tail membrane. Body shedding rate and sperm motility have been significantly increased mortality. KF-950 can affect the sperm function by disrupting the sperm membrane.