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目的探讨先天性巨结肠症(HD)合并神经节细胞减少(HYP)与术后肠炎发生的相关性。方法对97例在我院行巨结肠根治术的患儿进行随访,随访时间1.5～8年,平均3.4年。分为两组:A组70例,为HD;B组27例,为HD合并HYP。对其排便功能与术后小肠结肠炎(EC)的发生情况进行分析比较。结果A组术后发生肠炎有8例(11.4%),B组发生肠炎有11例(40.7%),两组相比较差异有统计学意义(P<0.005)。按照李正的评分系统,A组排便功能评分为优者比率为85.7%,明显高于B组的62.9%(P<0.05)。A组便秘复发率为2.9%(2/70),B组为14.8%(4/27),但两者之间差异无统计学意义(P>0.05)。结论HD合并HYP患儿术后较HD更易发生小肠结肠炎,完全切除HYP肠管可降低EC的发生率,减轻肠炎发生的程度。
Objective To investigate the relationship between Hyphema H pylori (HD) and ganglion cell reduction (HYP) and postoperative enteritis. Methods 97 cases of Hirschsprung radical hysterectomy in our hospital were followed up for 1.5 to 8 years, an average of 3.4 years. Divided into two groups: A group of 70 cases, HD; B group of 27 cases, HD with HYP. The defecation function and postoperative enterocolitis (EC) were analyzed and compared. Results There were 8 cases (11.4%) of enteritis in group A and 11 (40.7%) cases of enteritis in group B. There was significant difference between the two groups (P <0.005). According to Li Zheng’s scoring system, the defecation function score of group A was 85.7%, which was significantly higher than that of group B (62.9%, P <0.05). The recurrence rate of constipation was 2.9% (2/70) in group A and 14.8% (4/27) in group B, but there was no significant difference between them (P> 0.05). Conclusions HD combined with HYP is more likely to enter enterocolitis than HD, and complete resection of HYP can reduce the incidence of EC and reduce the incidence of enteritis.