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维甲酸能阻断造血祖细胞向嗜酸粒细胞及肥大细胞的定向分化 ,抑制B细胞增殖 ,有抑制炎症发生的作用 ;维甲酸能促进体内TH2 优势应答的发生 ,表现一定的促进炎症效应 ;维甲酸对粘附分子的表达与细胞类型有关 ,但目前尚未明确对肺部细胞黏附分子表达的影响 ,属不确定因素 ,所以评价维甲酸用于哮喘治疗的应用价值有待于对多种作用整体效应的综合研究。
Retinoic acid can inhibit the directional differentiation of hematopoietic progenitor cells into eosinophils and mast cells, inhibit the proliferation of B cells and inhibit the occurrence of inflammation. Retinoic acid can promote the occurrence of TH2 dominant response in vivo, which can promote the inflammatory effect. Retinoic acid on the expression of adhesion molecules and cell types, but the impact of lung cell adhesion molecule expression is not yet clear, is an uncertain factor, so evaluation of retinoic acid for the treatment of asthma to be the value of a variety of effects on the whole Comprehensive effect of the study.