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在过去的10~15年,由于新的“组学”技术的发展对微生物群落的遗传和代谢谱进行大规模的分析,人们对肠道菌群组成和功能的认识呈指数增长,从而为揭示肠道菌群的调节及其对机体的影响提供参考。肠道菌群像一个免疫系统与宿主协同工作,促进健康,但有时可能引发疾病。研究对肠道菌群领域现有观点进行总结和梳理,就菌群对宿主健康的潜在影响以及益生菌、益生元和多酚对肠道菌群的调节作用展开综述。
In the past 10-15 years, due to the development of new “genomics” technologies, large-scale analysis of the genetic and metabolic profiles of microbial communities has led to an exponential increase in the understanding of gut flora composition and function In order to reveal the regulation of intestinal flora and its impact on the body to provide a reference. Intestinal flora, like an immune system, works in concert with the host to promote health, but sometimes it can cause illness. The review summarizes and defragments current perspectives in the field of gut microbiota and reviews the potential impact of microbiota on host health and the regulatory role of probiotics, prebiotics and polyphenols on gut microbiota.