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胰岛素依赖型糖尿病（ＩＤＤＭ）的病因尚未明确，目前多数学者认为ＩＤＤＭ是在一定的遗传背景基础上，通过环境因素的作用诱发免疫机制的紊乱而发病。虽然诱发ＩＤＤＭ的环境因素以及引起自身免疫反应的始动抗原尚未明确，但关于胰岛β细胞破坏机制的研究发展很快，发现了一
The etiology of insulin-dependent diabetes mellitus (IDDM) is not yet clear. At present, most scholars think that IDDM is based on a certain genetic background and causes the disturbance of immune mechanism by the action of environmental factors. Although the environmental factors that induce IDDM and the initiating antigens that cause autoimmune reactions are not yet clear, the research on the mechanism of islet beta cell destruction has been rapidly developed.