一般认为细胞介导的免疫对于控制人的巨细胞病毒(CMV)感染起主要作用,通常用 CMV 抗原诱导的淋巴细胞增殖试验、来测定。这种试验是在含少量 CMV 特异性抗体的混合人血清的条件下进行的。而该抗体在试验中的作用还不了解。本文作者应用不同的 CMV 抗原(粗制不含细胞的 CMV,部分纯化的 CMV 及含有细胞的 CMV)和一种包括白喉与破伤风类毒素,白色念珠菌和纯化的蛋白衍生物的回忆性抗原,详细地研究了 CMV 抗体对 CMV 特异性淋巴细胞反应 Cell-mediated immunity is generally believed to play a major role in the control of human cytomegalovirus (CMV) infection and is usually measured using the CMV antigen-induced lymphocyte proliferation assay. This test is carried out with mixed serum containing a small amount of CMV-specific antibody. The role of the antibody in the experiment is not understood. The authors applied different CMV antigens (crude cell-free CMV, partially purified CMV and cell-containing CMV) and a recall antigen including diphtheria and tetanus toxoid, Candida albicans and purified protein derivatives , CMV-specific lymphocyte responses to CMV were studied in detail