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目的 :探讨静脉滴注刺五加并腰穿脑脊液置换术防治蛛网膜下腔出血 (SAH )后脑血管痉挛 (CVS)及缓解SAH后头疼的疗效。方法 :将 42例SAH随机分为两组 ,对照组 ( 2 2例 ) ,治疗组 ( 2 0例 )。对照组采用常规内科治疗 ,治疗组在常规治疗的基础上采用静脉滴注刺五加并行腰穿脑脊液置换术。结果 :治疗组头痛持续的时间较对照组缩短 ,具有统计学意义 (P <0 0 1)。治疗组、对照组CVS的发生率分别为 15 %、3 7 5 %。死亡率分别为 10 %、3 6 5 % ,经统计学处理有显著性差异 (P <0 0 5 )。结论 :静脉滴注刺五加并行腰穿脑脊液置换术优于常规内科治疗 ,可有效的缓解SAH后头痛 ,减轻症状。且防治SAH后CVS安全有效 ,能促进神经功能的尽快恢复。
Objective: To investigate the curative effect of intravenous infusion of acanthopanax senticosus plus lumbar penetrating cerebrospinal fluid replacement on prevention of cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) and relief of headache after SAH. Methods: 42 cases of SAH were randomly divided into two groups, the control group (22 cases), the treatment group (20 cases). The control group received routine medical treatment, and the treatment group was treated with intravenous drip plus five plus concurrent lumbar puncture and cerebrospinal fluid replacement on the basis of routine treatment. Results: The duration of headache in the treatment group was shorter than that in the control group, with statistical significance (P <0.01). The incidence of CVS in the treatment group and control group were 15% and 375% respectively. Mortality rates were 10% and 36.5%, respectively, with significant differences (P <0.05) by statistical analysis. Conclusion: Intravenous infusion of Acanthopanax senticosus plus lumbar puncture and cerebrospinal fluid replacement is superior to conventional medical treatment, which can effectively relieve headache and relieve symptoms after SAH. And after the prevention and treatment of SAH CVS safe and effective, can promote the recovery of nerve function as soon as possible.