论文部分内容阅读
用频数配比和两个对照组的病例－对照研究方法，分析了丙型肝炎病毒（ＨＣＶ）感染和某些致病因子在肝癌发病中的作用．频数配比的条件为同年龄（±３岁）、同性别、同居住地、病例组的抗－ＨＣＶ阳性率为１５．６０％（１７／１０９）．两个对照组分别为６．４２％（７１／１０９）和１．８３％（２／１０９）．差异均有显著性（Ｐ＜０．０５）。排除输血混杂因素后，病例组与对照组之间，ＨＣＶ感染仍有显著性差异（Ｐ＜０．０５）。经多因素Ｌｏｇｉｘｔｉｃ回归分析．ＨＣＶ感染在病例组和两个对照组间的ＯＲ值分别为９．１８和４２。１８．在肝癌病因中ＨＢＶ感染的病因分值（０．８１６６～Ｏ．８６４１）大于ＨＣＶ感染（０。０９４８～０．１３９４）。
The role of hepatitis C virus (HCV) infection and some virulence factors in the pathogenesis of hepatocellular carcinoma was analyzed using frequency-matching and case-control studies in two control groups. The frequency of the ratio of the conditions for the same age (± 3 years), the same sex, the same place of residence, case group anti-HCV positive rate was 15.60% (17/109). The two control groups were 6.42% (71/109) and 1.83% (2/109). The differences were significant (P<0.05). Excluding transfusion confounding factors, there was still a significant difference in HCV infection between the case group and the control group (P<0.05). Multivariate Logixtic regression analysis. The OR values of HCV infection between the case group and the two control groups were 9.18 and 42.18. The etiological score of HBV infection in the etiology of liver cancer (0.8166-O.8641) was greater than that of HCV infection (0. 0948-0.1394).