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本文报告18例慢性小管间质性肾炎,并分析其临床与实验室资料,结果表明感染与药物损伤为本病的主要原因,本病的突出临床表现是由于肾脏的浓缩与酸化功能障碍,常表现为多尿多饮及肾小管性酸中毒并伴有氮质血症、骨营养不良及贫血。文中讨论了慢性 TIN 的发病机制及临床诊断指标,认为虽无病理组织学资料,而凭临床资料亦能作出诊断。
This article reports 18 cases of chronic tubulointerstitial nephritis, and analysis of clinical and laboratory data, the results show that the main reason for the infection and drug damage-based disease, the outstanding clinical manifestations of this disease is due to kidney condensation and acidification dysfunction, often The performance of polyuria and alcoholysis and renal tubular acidosis associated with azotemia, osteodystrophy and anemia. This article discusses the pathogenesis of chronic TIN and clinical diagnostic indicators, that although no histopathological data, but with clinical data can make a diagnosis.