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目的探讨阿奇霉素静脉滴注加阴道冲洗治疗生殖道支原体感染的效果。方法选择2014年4月-2016年4月于东北师范大学校医院就诊的生殖道支原体感染且药敏试验对阿奇霉素敏感的患者67例,随机分为对照组(31例)和实验组(36例)。两组患者均采用阿奇霉素静脉滴注,0.5 g/次,1次/d,疗程14 d;实验组同时加用阿奇霉素0.25 g阴道冲洗作为辅助治疗,1次/d,连续7 d。结果实验组治疗总有效率(97.22%)高于对照组(80.64%),差异有统计学意义(P<0.05)。结论阿奇霉素静脉滴注加阴道冲洗治疗生殖道支原体感染效果好、安全、方便。
Objective To investigate the effect of azithromycin intravenous drip plus vaginal irrigation on mycoplasma genital tract infection. Methods 67 cases of azithromycin-susceptible patients with mycoplasma genitalium infection from April 2014 to April 2016 in Northeast Normal University Hospital were randomly divided into control group (31 cases) and experimental group (36 cases ). The two groups of patients were treated with azithromycin 0.5 g once daily for 14 days. The patients in the experimental group received 0.25 g vaginal washing with azithromycin once a day for 7 days. Results The total effective rate of experimental group (97.22%) was higher than that of control group (80.64%), the difference was statistically significant (P <0.05). Conclusion Azithromycin intravenous infusion plus vaginal irrigation treatment of genital Mycoplasma infection is effective, safe and convenient.