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目的 :研究甲亢病患者的骨代谢改变及其发生机理。方法 :检测甲亢病初治患者TT3、TT4、TGA、TMA ,血清游离钙(Ca )、磷(P)、及24h尿钙(Ca)、P排量 ;测量非用力前臂桡、尺骨下1/3位点的骨密度与对照组作对比研究。结果 :25例初治甲亢病患者TGA、TMA均为阳性 ,血清游离钙(Ca )、磷(P)、及24h尿钙(Ca)、P排量均显著高于正常对照组。前臂骨量较对照组显著减少。结论 :高甲状腺素血症及自身免疫损伤可致骨密度减低
Objective: To study the changes of bone metabolism and its mechanism in patients with hyperthyroidism. Methods: TT3, TT4, TGA, TMA, serum free calcium (Ca), phosphorus (P) and 24h urinary calcium (Ca) and P were measured in patients with primary Hyperthyroidism. Radiofrequency ablation, 3-point bone mineral density compared with the control group for comparative study. Results: TGA and TMA were positive in 25 cases of newly diagnosed hyperthyroidism patients. Serum Ca, P, and 24 hours urinary calcium (Ca), P were significantly higher than those in normal controls. Forearm bone mass was significantly reduced compared with the control group. Conclusion: Hypothyroidism and autoimmune damage can result in decreased bone mineral density