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目的观察息宁（左旋多巴／卡比多巴）对难治性屈光参差性弱视患儿拥挤现象及双眼间相互作用的影响，探讨左旋多巴治疗弱视的机理。方法给３２名５～１５岁、经传统方法治疗至少６个月无效的屈光参差性弱视患儿口服息宁，每公斤体重左旋多巴１ｍｇ、卡比多巴０２５ｍｇ，每日３次，连续６０天。观察分析服药后单字Ｅ、拥挤Ｅ字视力和分视ＶＥＰＢ／Ｍ值的变化。结果（１）弱视眼及优势眼单字、拥挤视力之差变化均无显著性（Ｐ＞００５）。（２）Ｂ／Ｍ值在服药前后变化无显著性（Ｐ＞００５）。结论左旋多巴对弱视分视ＶＥＰ表现的异常双眼间相互作用无显著影响，认为左旋多巴治疗弱视的机理是解除视觉抑制的假设尚待进一步研究证实。
Objective To observe the effect of ning ning (levodopa / carbidopa) on crowding in children with refractory anisometropic amblyopia and the interaction between eyes, and to explore the mechanism of levodopa in treating amblyopia. Methods 32 patients aged 5-15 years with refractory atypical myopia of amblyopia with amblyopia of at least 6 months who were treated by traditional methods were given 1 mg levodopa per kg body weight and 025 mg carbidopa per day for 3 times For 60 consecutive days. Observe and analyze the change of single word E, crowded E word visual acuity and partial visual VEPB / M value after taking medicine. Results (1) There was no significant difference between eyes with amblyopia and eyes with dominant eyes, crowding sight (P> 005). (2) There was no significant difference in B / M before and after taking the drug (P> 0.05). Conclusions Levodopa has no significant effect on the abnormal binocular interaction between amblyopia and VEP. It is believed that the mechanism of levodopa in treating amblyopia is to relieve the supposition of visual inhibition, which needs further study.