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结蛋白(desmin)是在肌细胞发生中产生的,分子量53,000。见于平滑肌,骨胳肌的Z带、心肌的Z带和间盘,是骨胳肌、平滑肌的特异性中间丝。本文检测了desmin在胎儿和成人多种正常组织及人体肿瘤中的分布、探讨其对肌源性肿瘤的诊断、分化程度的特异性和实用价值。
Desmin is produced during myogenesis and has a molecular weight of 53,000. Seen in smooth muscle, the Z band of the skeletal muscle, the Z band of the myocardium, and the intervertebral disc are the specific intermediate filaments of the skeletal muscle and smooth muscle. This article examines the distribution of desmin in various normal tissues and human tumors in fetuses and adults, and explores the specificity and practical value of desmin for the diagnosis and differentiation of myogenic tumors.