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目的探究在晚期膀胱癌合并出血患者的治疗过程中应用双侧髂内动脉化疗栓塞治疗的效果。方法纳入2015年1月至2016年10月重庆三峡中心医院收治的60例晚期膀胱癌合并出血的患者,随机分为2组,每组各30例。观察组患者给予双侧髂内动脉化疗栓塞治疗,对照组患者给予常规灌注化疗。记录2组患者血尿缓解所需时间和并发症发生情况。结果观察组患者在治疗后出血停止所需时间明显少于对照组,差异有统计学意义(P<0.05);在相应方案治疗期间,2组患者的不良反应发生情况比较,差异无统计学意义(P>0.05)。结论双侧髂内动脉化疗栓塞治疗晚期膀胱癌合并出血患者,其有效性、安全性均较优,有利于保障患者的生活质量和生命安全。
Objective To investigate the effect of bilateral internal iliac artery chemotherapy and embolization in the treatment of advanced bladder cancer with hemorrhage. Methods Sixty patients with advanced bladder cancer complicated with hemorrhage admitted from Chongqing Three Gorges Central Hospital from January 2015 to October 2016 were randomly divided into two groups of 30 cases each. Patients in the observation group received bilateral internal iliac artery chemoembolization and patients in the control group received conventional infusion chemotherapy. Record the time and complications of hematuria in 2 groups of patients. Results The observation group patients stopped bleeding after treatment, the time required for treatment was significantly less than the control group, the difference was statistically significant (P <0.05); during the corresponding program treatment, two groups of patients with adverse reactions, the difference was not statistically significant (P> 0.05). Conclusion Bilateral internal iliac artery chemoembolization in the treatment of patients with advanced bladder cancer complicated with hemorrhage has better efficacy and safety, which is good for ensuring the quality of life and safety of patients.