多器官衰竭是创伤和其它严重疾病的重要死亡原因。肠系膜缺血或再灌注使肠道粘膜屏障功能受损导致细菌或内毒素从肠道移位,可能在多器官衰竭的发生中起重要作用。肠系膜缺血常见于各种原因的休克,复苏和再灌注能加重缺血引起的损伤。肠道损伤引起的局部炎 Multiple organ failure is an important cause of death from trauma and other serious illnesses. Mesenteric ischemia or reperfusion impairs intestinal barrier function leading to bacterial or endotoxin translocation from the intestine and may play an important role in the development of multiple organ failure. Mesenteric ischemia is common in various causes of shock, resuscitation and reperfusion can aggravate ischemia-induced injury. Local inflammation caused by intestinal injury