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以往曾有报告,小白鼠注射成虫浸出液获得了对曼氏血吸虫的轻微防御力,或注射尾蚴和成虫的培养液延长了小白鼠的存活。但是有些作者用虫卵、尾蚴和成虫诱发对曼氏血吸虫的防御力都未成功。本文作者认为功能性抗原可能是很不稳定的,因而设想用宿主体内被UK_(3883)(2-异丙基甲基-6-甲基-7-硝基-1,2,3,4四氢化喹啉)杀死的曼氏血吸虫幼虫免疫小白鼠。UK_(3883)是杀死曼氏血吸虫和发育期幼虫很
In the past, it has been reported that mice injected with adult leachate obtained a slight defense against Schistosoma mansoni, or coccidiosis and adult cercariae injection prolonged the survival of the mice. However, some authors have not succeeded in killing Schistosoma mansoni with eggs, cercariae and adults. The authors believe that functional antigens may be very unstable, so it is envisaged that the host will be treated with UK_ (3883) (2-isopropylmethyl-6-methyl-7-nitro-1,2,3,4-tetrakis Hydrogenated quinoline) killed Schistosoma mansoni larvae immunized mice. UK_ (3883) is killed by Schistosoma mansoni and larvae