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目的探讨孕妇妊娠晚期贫血对新生儿出生身长、体重、孕周以及一分钟Apgar评分的影响并研究孕妇血红蛋白含量与新生儿脐血中血清铁含量之间的关系。方法以2008年12月～2009年8月在某院住院分娩的孕妇及其分娩的新生儿作为研究对象,采用历史前瞻性队列研究方法收集孕妇孕期保健、住院分娩和妊娠结局资料。结果孕妇妊娠晚期血红蛋白含量与新生儿出生身长、体重、孕周呈线性相关,中、重度贫血组孕妇的新生儿出生身长小于正常对照组新生儿出生身长。随着孕妇贫血程度加重,新生儿早产、低出生体重发生率呈上升趋势。结论孕妇妊娠晚期贫血,尤其是中、重度贫血对新生儿妊娠结局可能存在负面影响。
Objective To investigate the effect of pregnant women with anemia in the third trimester on neonatal birth size, body weight, gestational age and one-minute Apgar score and to study the relationship between hemoglobin levels in pregnant women and serum iron levels in newborn umbilical cord blood. Methods Pregnant women and their newborn babies born in a hospital from December 2008 to August 2009 were enrolled in this study. A prospective historical cohort study was conducted to collect data on pregnant women ’s health during pregnancy, hospital delivery and pregnancy outcomes. Results The hemoglobin content of pregnant women in the third trimester of pregnancy was linearly correlated with the length, weight and gestational age of newborns. The birth weight of newborns in pregnant women with moderate and severe anemia was smaller than that of normal controls. With the aggravating degree of anemia in pregnant women, the incidence of premature birth and low birth weight of newborn babies is on the rise. Conclusion Pregnant women with anemia in late pregnancy, especially in moderate and severe anemia may have a negative impact on neonatal pregnancy outcome.