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目的探讨危重病患者血清乳酸(Lactic Acid)水平变化的临床意义及与预后的关系。方法对2015年1月~2016年1月我院ICU132名危重症患者进行回顾性分析,分析其血清乳酸水平,根据乳酸水平将患者分为4组。探讨不同的乳酸水平与血PH值、碱剩余(BE)及患者死亡率的关系。结果 132名危重患者有85例血清乳酸升高,占总数的64.39%,血Lac增高危重症患者死亡率较血Lac正常组明显增高(P<0.01);血Lac水平越高,死亡率越高。血Lac>12,死亡率明显增高(P<0.001)。同时显示:血Lac水平与PH值呈负相关,血Lac水平愈高,PH值愈低。相关系数-0.8738,P<0.001。结论危重病患者中,血LAC测定有助于了解组织细胞的缺氧情况。血LAC浓度的变化与血PH变化有良好相关性,血LAC的变化可以反映病情变化,它是判定预后的一个重要指标。
Objective To investigate the clinical significance of serum Lactic Acid level in critically ill patients and its relationship with prognosis. Methods From January 2015 to January 2016, 132 critically ill patients with ICU in our hospital were retrospectively analyzed. The serum lactic acid level was analyzed. Patients were divided into 4 groups according to the level of lactic acid. To investigate the relationship between different levels of lactic acid and blood PH value, base residue (BE) and patient mortality. Results Serum Lactic acid was increased in 85 of 132 critically ill patients, accounting for 64.39% of the total. The mortality of critically ill patients with elevated serum Lac was significantly higher than that of the normal Lac group (P <0.01). The higher the blood Lac level, the higher the mortality rate . Blood Lac> 12, mortality was significantly higher (P <0.001). At the same time showed: blood Lac levels and PH value was negatively correlated, the higher the blood Lac level, the lower the PH value. Correlation coefficient -0.8738, P <0.001. Conclusion Serum LAC in critically ill patients is helpful to understand the hypoxia of tissue cells. Blood LAC concentration changes and blood PH changes have a good correlation, changes in blood LAC can reflect the condition changes, it is to determine the prognosis of an important indicator.