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目的了解长沙地区不同类型禽类职业暴露人群高致病性禽流感H5N1亚型病毒的抗体分布状况,分析不同职业暴露人群H5N1感染的风险性。方法采集菜市场家禽屠宰零售人员、大型家禽饲养企业工人和农村个体家禽散养人员的血清标本,用单放射免疫扩散溶血技术(SRH)检测H5N1抗体。结果市场零售人员、农村个体家禽散养人员、企业饲养人员H5N1感染率分别为25%、1%和1.92%,男性从业人员H5N1抗体阳性率为10%,女性为23.88%。结论市场零售人员感染H5N1风险性远高于农村散养人员和企业饲养人员,不同职业人员中女性H5N1抗体阳性率高于男性从业人员。
Objective To understand the antibody distribution of H5N1 subtype virus of HPAI in different occupational exposure groups in Changsha area and to analyze the risk of H5N1 infection in different occupational exposure groups. Methods Serum samples of poultry slaughter and retailers, large-scale poultry breeding workers and individual poultry free-rangers in rural areas were collected, and H5N1 antibodies were detected by single radioimmunoassay and hemolysis (SRH). Results The prevalence of H5N1 infection was 25%, 1% and 1.92% respectively in retailers, rural independent poultry workers and stockbreeding workers. The positive rate of H5N1 antibody was 10% in male employees and 23.88% in women. Conclusion The risk of H5N1 infection among retailers in the market is far higher than that of rural free-range workers and enterprise breeders. The positive rate of H5N1 antibody in different occupations is higher than that of male employees.