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目的观察支气管肺发育不良(BPD)患儿肺功能变化。方法采用婴幼儿体描箱检测并比较BPD患儿31例(A组)和40例健康婴幼儿(C组)达峰容积(VPEF)/呼气容积(VE)比值、达峰时间(TPTEF)/呼气时间(TE)比值、功能残气量(FRC)、有效气道阻力(Reff)、呼吸频率(RR)和每千克体重呼吸系统静态顺应性(Crs/kg)等肺功能指标。结果 A组VPEF/VE和TPTEF/TE比值、FRC和Crs/kg均低于C组,而Reff和RR高于C组(P<0.05)。两组其余肺功能指标相仿(P>0.05)。结论 BPD患儿均存在气道阻塞和肺功能下降。体描箱可作为检测BPD患儿肺功能的重要手段。
Objective To observe the changes of pulmonary function in children with bronchopulmonary dysplasia (BPD). Methods Totally 31 children with BPD (group A) and 40 healthy infants (group C) were enrolled in this study. The ratio of peak volume (VPEF) / expiratory volume (VE) / Expiration (TE) ratio, functional residual capacity (FRC), effective airway resistance (Reff), respiratory rate (RR) and respiratory compliance (Crs / kg) per kg body weight. Results The ratio of VPEF / VE to TPTEF / TE, FRC and Crs / kg in group A were lower than those in group C, while Reff and RR were higher than those in group C (P <0.05). The remaining lung function indicators were similar (P> 0.05). Conclusions Airway obstruction and pulmonary function decline exist in children with BPD. Body contour box can be used as an important measure of pulmonary function in children with BPD.