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目的:探讨血浆同型半胱氨酸(Hcy)水平与冠状动脉病变的相关性及Hcy与冠脉急性病变的关系。方法:对90例行冠脉造影的患者检测血浆Hcy,比较病变支数、冠心病不同类型的血浆Hcy水平。结果:冠心病组的血浆Hcy水平高于非冠心病组;随着冠脉病变支数的增多,血浆Hcy水平依次升高;急性冠脉综合征组血浆Hcy水平高于稳定型心绞痛组。结论:Hcy水平与冠脉病变支数、严重程度相关,与冠脉急性病变有关。
Objective: To investigate the relationship between plasma homocysteine (Hcy) level and coronary artery disease and the relationship between Hcy and acute coronary lesions. Methods: Plasma Hcy levels were measured in 90 patients undergoing coronary angiography. The lesion count, plasma Hcy levels in different types of coronary heart disease were compared. Results: Plasma homocysteine level in CHD group was higher than that in non-CHD group. Plasma homocysteine level increased with the increase of coronary artery lesion number. Hcy level in acute coronary syndrome group was higher than that in stable angina group. Conclusion: The level of Hcy is related to the number and severity of coronary lesions and is related to acute coronary lesions.