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答:儿童用药剂量的计算方法很多,如:柯氏(Cowling)公式、克氏(Clark)公式、杨氏(Young)公式、费氏(Fried)公式(计算1周岁以下儿童剂量用)、老幼剂量按成人剂量折算法、以每公斤体重为用药单位的计算法等。近几年来,有些方法如杨氏公式、柯氏公式已逐渐少用,因用以上方法计算所得的剂量往往不能适合临床治疗需要。例如磺胺嘧啶,中国药典1963年版规定的成人口服常用剂量一次0.5～1.0克,一日3.0～6.0克。以一周岁儿童为例,用各方法计算其剂量如下:
A: There are many ways to calculate the dose of medicine for children, such as the Cowling formula, the Clark formula, the Young formula, the Fried formula (for calculating the dose for children under 1 year old), the old Young dose by adult dose conversion method, per kilogram of body weight for the unit of calculation and so on. In recent years, some methods such as Young’s formula, Koch’s formula has gradually less use, because the above method of calculating the dose often can not be suitable for clinical treatment needs. For example, sulfadiazine, Chinese Pharmacopoeia 1963 version of the commonly used adult oral dose of 0.5 to 1.0 grams, 3.0 to 6.0 grams a day. Taking one-year-old children as an example, calculate the dosage by the following methods: