３位科学家因发现ＮＯ活性荣获１９９８年度诺贝尔奖。１９７７年Ｍｏｒａｄ发现硝酸甘油释放Ｎｏ，Ｎｏ松弛血管平滑机。Ｆｕｒｃｈｇｏｔｔ的研究始于１９８０年，后来确认ＮＯ是一种具生物活性物质，提出内皮细胞产生一种不知名的信号分子，松弛血管平滑肌，称之为内皮衍生 Three scientists won the 1998 Nobel Prize for finding NO activity. In 1977 Morad found that Nitroglycerin releases No, No relaxing vascular smoothing machine. Furchgott’s study began in 1980 and later identified NO as a biologically active substance, suggesting that endothelial cells produce an unknown signal molecule that relaxes vascular smooth muscle, termed endothelium-derived