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2 改变脂蛋白分布的药物 HDL的抗动粥硬作用经实验证明(Miller等,1975)已受到广泛的注意。绝经期前妇女,血HDL含量高于同年龄的男性,而患冠心病者少。家族性高α脂蛋白血症者很少发生冠心病而且长寿(Glweck等,1975)。我国人(庄汉忠等1981)和日本人(yano等1980)血HDLc含量较西方人高,而冠心病相对也较少。HDL的密度(d=1.063-1.210)有HDL_2(d=1.063-1.125)和HDL_3(d=1.125-1.210)亚组分,HDL_2浓度增高或HDL_2/HDL_3比值增大时较少发生动粥硬和冠心病,提示如能使血HDL含量,特别是使HDL_2的含量增高,将是防治动粥硬的新途径。
2 Lipoprotein-Altering Drugs The anti-porcini effect of HDL has been experimentally demonstrated (Miller et al., 1975) that extensive attention has been paid. Premenopausal women, blood HDL levels higher than men of the same age, and less coronary heart disease. Familial hyperlipoproteinemia is less likely to develop coronary heart disease and longevity (Glweck et al., 1975). My people (Zhuanghanzhong et al. 1981) and Japanese (yano et al 1980) have higher HDLc levels in the blood than in the westerners and relatively fewer coronary heart disease. The density of HDL (d = 1.063-1.210) was lower in HDL_2 (d = 1.063-1.125) and HDL_3 (d = 1.125-1.210) subgroups than in HDL_2 or HDL_2 / HDL_3 Coronary heart disease, if prompted to make the content of blood HDL, in particular, to increase the content of HDL_2, will be the prevention and treatment of porridge hard new way.