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目的:比较沐舒坦注射液在5％葡萄糖注射液,0．9％氯化钠注射液,乳酸林格氏注射液中的稳定性。方法:在沐舒坦注射液加入输液6 h内,采用HPLC法测定盐酸氨溴索的含量,采用pH计测定输液pH值,并肉眼观察输液的颜色和澄明度。结果:在沐舒坦注射液加入输液6 h内,盐酸氨溴索的含量和pH值均保持稳定,输液的颜色和澄明度也未发生变化。结论:沐舒坦注射液的在3种常用输液中是稳定的。
OBJECTIVE: To compare the stability of Mucosolvan injection in 5% dextrose injection, 0.9% sodium chloride injection and lactated Ringer’s injection. Methods: Ambroxol injection was added into the infusion within 6 h, the content of ambroxol hydrochloride was determined by HPLC, the pH value of the infusion was measured by pH meter, and the color and clarity of infusion were observed visually. Results: The content and pH value of ambroxol hydrochloride remained unchanged within 6 h after the infusion of ambroxol and the infusion color and clarity did not change. Conclusion: Mucosolvan injection is stable in 3 common infusions.