直肠癌容易发生肝脏和肺的转移,直肠癌合并远处转移的治疗是临床难题,既往有文献报告肺转移灶不能完全切除的直肠癌患者的中位生存期仅有9个月[1]。近年来,随着化疗药物和各种分子靶向药物的迅猛发展,合并远处转移的直肠癌患者的生存期有了显著的提高。本文报告我科收治的1例直肠癌患者,患者虽然在就诊时已经合并肺转移癌,但在经过放化疗、手术、生物靶向治疗等综合治疗后获得长期生存,目前其生存期已经超过3年。 Rectal cancer prone to liver and lung metastases, the treatment of rectal cancer combined with distant metastasis is a clinical problem, the previous literature reports of lung metastases can not be completely resected rectal cancer patients with median survival of only 9 months [1]. In recent years, with the rapid development of chemotherapy drugs and various molecular targeted drugs, the survival of rectal cancer patients with distant metastasis has been significantly improved. This article reports a case of rectal cancer patients admitted to our department, although patients already have lung metastasis at the time of treatment, but after long-term survival after radiotherapy and chemotherapy, surgery, bio-targeted therapies and other comprehensive treatment, the current survival time has more than 3 year.