论文部分内容阅读
目的探讨非小细胞肺癌(NSCLC)与血清同型半胱氨酸(Hcy)的关系。方法采用病例-对照研究设计,分别检测45例NSCLC(研究组)及45例健康者(对照组)的血清Hcy水平及高Hcy(HHcy)的检出率。结果研究组Hcy水平17.5±5.9μmol/L,明显高于对照组的12.8±4.1μmol/L(P<0.01),研究组HHcy检出率40.0%亦明显高于对照组的17.8%(P<0.05)。结论 NSCLC患者血清Hcy水平升高,且检出率较高,提示NSCLC与Hcy有着密切的联系。
Objective To investigate the relationship between non-small cell lung cancer (NSCLC) and serum homocysteine (Hcy). Methods The case-control study design was used to detect the serum Hcy level and the high Hcy (HHcy) detection rate in 45 NSCLC (study group) and 45 healthy controls (control group) respectively. Results The Hcy level in study group was significantly higher than that in control group (17.5 ± 5.9μmol / L, 12.8 ± 4.1μmol / L, P <0.01). The detection rate of Hcy in study group was also significantly higher than that of control group by 40.0% (P < 0.05). Conclusion Serum Hcy levels are elevated in patients with NSCLC, and the detection rate is high, suggesting that there is a close relationship between NSCLC and Hcy.