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[目的]探讨潮汕地区食管和食管胃交界处恶性肿瘤临床病理特征。[方法]收集1954￣2006年潮汕地区16954例食管和食管胃交界处恶性肿瘤临床病理资料,使用SPSS11.5软件对其性别、年龄、发病部位及病理类型等特点进行分析。[结果]16954例病例中,食管恶性肿瘤11996例(占70.8%),食管胃交界处恶性肿瘤4958例(占29.2%)。食管恶性肿瘤和食管胃交界处恶性肿瘤的男女之比分别为3.06∶1和4.63∶1。食管恶性肿瘤平均发病年龄是55.93岁,食管胃交界处恶性肿瘤的平均发病年龄是59.76岁。食管恶性肿瘤发病部位以食管中段(69.74%)最多见,其次为食管下段(16.91%)与食管上段(13.32%)。食管恶性肿瘤的大体类型主要为溃疡型(44.82%),其次为髓质型(37.29%)。组织学类型上,食管恶性肿瘤以鳞癌为主(95.47%),其次为腺癌(3.234%);食管胃交界处恶性肿瘤以腺癌为主(95.22%),其次为鳞癌(3.53%)。[结论]食管和食管胃交界处恶性肿瘤作为广东潮汕地区最常见的恶性肿瘤,在男女发病比例、发病年龄、大体类型和组织学类型等临床病理特点方面,潮汕地区与国内其他高发地区比较相一致。
[Objective] To explore the clinicopathological features of malignant tumors at the junction of esophagus and esophagus and stomach in Chaoshan area. [Methods] The clinical and pathological data of 16 954 esophageal and esophagogastric junction tumors in the Chaoshan region from 1954 to 2006 were collected. The characteristics of the sex, age, disease site and pathological type were analyzed by SPSS 11.5 software. [Results] Of the 16 954 cases, 11 996 (70.8%) had esophageal malignancies, and 4958 (29.2%) had esophageal and gastric malignancies. The ratio of men to women for esophageal and esophageal malignancies was 3.06: 1 and 4.63: 1, respectively. The average age of onset of esophageal malignancies was 55.93 years, the average age of onset of malignant tumors at the esophagogastric junction was 59.76 years. The incidence of esophageal malignancies in the middle part of the esophagus (69.74%) the most common, followed by the lower esophagus (16.91%) and the upper esophagus (13.32%). The main types of esophageal cancer were mainly ulcer (44.82%), followed by medulla (37.29%). Histologically, the majority of esophageal malignant tumors were squamous cell carcinoma (95.47%), followed by adenocarcinoma (3.234%), adenocarcinoma (95.22%) esophagogastric junction, followed by squamous cell carcinoma (3.53% ). [Conclusion] Malignant tumors at the junction of esophagus and esophagogastric junction are the most common malignant tumors in Chaoshan area of Guangdong Province. Compared with other high incidence areas in China, Chaoshan area has more clinical and pathological features such as the proportion of male and female patients, the age of onset, general type and histological type Consistent.