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乙型肝炎病毒(HBV)感染呈世界性流行,是危害全人类健康的公共卫生问题,母婴垂直传播是HBV传播的主要途径之一。近年来,通过主被动联合免疫预防措施的普遍实施,HBV的母婴阻断取得了较好的效果,但仍有5%~10%的失败率,因此在阻断方案、失败原因、相关机制等方面仍存在亟待解决的问题。本文从分娩前、分娩时、分娩后各个阶段对目前乙肝母婴阻断的现状以及存在的争议性问题进行了综述。
Hepatitis B virus (HBV) infection is a worldwide epidemic, which is a public health problem that endangers the health of all mankind. Vertical transmission of mother to child is one of the main ways of HBV transmission. In recent years, through the implementation of active and passive joint immunization preventive measures, HBV has achieved good results in maternal and child blockade, but it still has a failure rate of 5% ~ 10%. Therefore, in terms of blocking scheme, failure reason, There are still problems to be solved urgently. This article reviews the status quo and the controversial issues of the current blockage of hepatitis B virus (HBV) before delivery, at delivery and after delivery.