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目的:比较头孢克洛和头孢克肟对小儿患者急性细菌性肠炎的临床疗效。方法:选取2015年2月—2016年2月期间收治的急性细菌性肠炎患儿100例,将其分为治疗组和参照组,每组50例;参照组患者均给予头孢克洛胶囊治疗,治疗组患者均给予头孢克肟胶囊治疗,在此基础之上给予两组患者适当的护理干预和辅助治疗,比较两组患儿治疗后的总有效率以及不良反应的发生率。结果:治疗组患者治疗后的治疗总有效率为96.00%高于参照组为82.00%(P<0.05);两组患者用药期间发生不良反应类型主要为过敏性皮炎、药疹、睡眠受阻和血液显色反应等,治疗组患者不良反应的发生率为10.00%低于参照组为34.00%(P<0.05)。结论:头孢克肟对小儿患者急性细菌性肠炎的临床疗效优于头孢克洛,且不良反应的发生率较低。
Objective: To compare the clinical efficacy of cefaclor and cefixime in children with acute bacterial enteritis. Methods: A total of 100 children with acute bacterial enteritis were selected from February 2015 to February 2016, divided into treatment group and reference group, 50 cases in each group. Patients in the reference group were given cefaclor capsules, Patients in the treatment group were treated with cefixime capsules. On the basis of this, appropriate nursing intervention and adjuvant therapy were given to both groups. The total effective rate and incidence of adverse reactions in both groups were compared. Results: The total effective rate after treatment was 96.00% in the treatment group and 82.00% in the reference group (P <0.05). The types of adverse reactions in the two groups were allergic dermatitis, drug eruption, obstruction of sleep and blood Color reaction, the incidence of adverse reactions in the treatment group was 10.00% lower than the reference group was 34.00% (P <0.05). Conclusion: The clinical efficacy of cefixime in children with acute bacterial enteritis is better than that of cefaclor, and the incidence of adverse reactions is low.