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本文报告43例急性心肌梗塞患者血浆cAMP和其中8例同时作cGMP的测定结果,提示急性心肌梗塞患者在发病24小时内血浆cAMP、cGMP含量比正常人有显著增高。作者认为心肌梗塞患者在发病24小时内检测cAMP,对了解早期严重并发症的预后有一定参考价值。本文还对急性心肌梗塞患者cAMP、cGMP含量的差异和cAMP/cGMP比值变化的临床意义以及cAMP升高的机理进行了初步讨论。
This paper reports 43 cases of acute myocardial infarction in patients with plasma cAMP and 8 cases of both cGMP determination results, suggesting that patients with acute myocardial infarction within 24 hours of onset of plasma cAMP, cGMP levels were significantly higher than normal. The authors believe that patients with myocardial infarction within 24 hours of onset of detection of cAMP, to understand the prognosis of early serious complications have some reference value. The paper also discussed the clinical significance of the difference of cAMP, cGMP content and cAMP / cGMP ratio in patients with acute myocardial infarction and the mechanism of cAMP elevation.