缩胆囊素（cholecystokinin,CCK）是一个具有广泛生物学活性的脑肠肽,它既是胃肠道主要调节激素之一,也作用于中枢神经系统,起着神经递质或调质的作用。研究表明,CCK参与摄食、胃肠运动、镇痛、情绪、记忆和睡眠等活动的调节及参与癫(?)、帕金森病等疾病的发生。本文综述近年来CCK在上述方面的研究进展。 Cholecystokinin (cholecystokinin, CCK) is a widely biological activity of ghrelin, which is not only one of the main gastrointestinal regulation of hormones, also act on the central nervous system, plays a neurotransmitter or the role of tempering. Studies have shown that CCK is involved in the regulation of food intake, gastrointestinal motility, analgesia, mood, memory and sleep activities, and is involved in the pathogenesis of epilepsy and Parkinson’s disease. This article summarizes the research progress of CCK in the above aspects in recent years.