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目的研究黄芩片的制备工艺,优选最佳工艺。方法以黄芩苷为指标,采用高效液相色谱法测定黄芩苷含量;采用单因素试验优选出黄芩苷的提取及制备工艺。结果最佳制备工艺是1cm长的黄芩加10+8倍的水,煎煮2次,每次2h,合并滤液,过滤,静置,用饱和明矾水溶液,使之沉淀完全,烘干,粉碎,加淀粉、硬脂酸镁适量,30%乙醇适量,制粒,压片,包糖衣。结论黄芩片的制备工艺合理。
Objective To study the preparation process of Huangqi tablets and optimize the best technology. Methods The baicalin content was determined by baicalin, and the content of baicalin was determined by high performance liquid chromatography. The extraction and preparation of baicalin were optimized by single factor experiment. Results The best preparation process is 1cm long Astragalus plus 10+8 times water, decocted 2 times, 2h each time, combined filtrate, filtered, and left standing, using saturated alum aqueous solution to complete precipitation, drying, crushing, Add starch, magnesium stearate, 30% ethanol, granulation, tableting, sugar coating. Conclusion The preparation process of Huangqi tablets is reasonable.