氟康唑(FCZ)是一种双三氮唑衍生物(图1),它对正常动物和免疫缺陷动物的实验性真菌感染都很有效,其特点是抗菌谱广,可以口服,吸收安全,组织器官内浓度较高,与血浆蛋白结合率低,毒副反应小,临床效果好,现将其近期研究进展简述如下。 Fluconazole (FCZ) is a bistriazole derivative (Figure 1) that is effective against experimental fungal infections in both normal and immunodeficient animals and is characterized by broad antibacterial spectrum that can be administered orally, safely, High concentrations of tissues and organs, low binding rate with plasma protein, small side effects, clinical effect is good, now its recent research progress is summarized as follows.