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目的了解黔南民族地区HIV感染者重叠感染丙型肝炎(HCV)、梅毒(TP)状况及其特点,为HIV/AIDS的防控和治疗提供科学依据。方法对2013年1月-2015年10月1 742例HIV确证阳性血清及621例普通体检人群HIV阴性血清标本,进行HCV及TP标志物检测。结果 HIV感染者HCV、TP及HCV+TP感染率均明显高于普通人群,差异有统计学意义(P<0.01)。不同性别HCV和TP的感染率差异均无统计学意义(P>0.05)。感染主要以农民、无业人员为主,不同文化程度以小学和初中为主,多集中在20岁~50岁,主要以已婚为主。不同民族TP感染率差异无统计学意义(P>0.05)。结论感染HIV时往往重叠丙型肝炎和梅毒的二重或多重感染,HIV/HCV混合感染明显低于HIV/TP混合感染。提示临床治疗HIV的同时,应注意丙型肝炎、梅毒多重感染的防治。
Objective To understand the prevalence and characteristics of hepatitis C virus (HCV) and syphilis (TP) in HIV-infected patients in Qiannan ethnic area and provide a scientific basis for the prevention and treatment of HIV / AIDS. Methods A total of 1 742 HIV-positive sera from January 2013 to October 2015 and HIV-negative sera from 621 general medical examinations were tested for HCV and TP markers. Results The infection rates of HCV, TP and HCV + TP in HIV-infected patients were significantly higher than those in the general population (P <0.01). There was no significant difference in the infection rates of HCV and TP between different sexes (P> 0.05). Mainly infected with peasants, unemployed people mainly to different levels of primary and junior high school education, mostly concentrated in the 20 to 50 years old, mainly married. There was no significant difference in TP infection rates among different ethnic groups (P> 0.05). Conclusions HIV infection often overlaps with hepatitis C and syphilis double or multiple infections, and HIV / HCV co-infection is significantly lower than HIV / TP co-infection. Tip of clinical treatment of HIV at the same time, should pay attention to hepatitis C, syphilis multiple infections prevention and treatment.