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目的了解不同体型人群的代谢异常情况。方法根据排除标准,从2009年中国健康与营养调查数据库10 241人的资料中筛选出7 849人纳入分析,收集社会人口学资料、人体测量指标及血清生化指标数据。按照BMI水平分为体重正常组、超重组和肥胖组,按照代谢状态分为代谢正常组和代谢异常组,结合体型和代谢状态分组产生6种表型,比较不同体型者代谢异常患病率及不同表型者体格和血清生化指标差异。结果纳入分析的7 849人中,超重及肥胖者分别为2 554例(32.54%)和822例(10.47%),代谢异常5 091例(占64.86%)。体重正常、超重和肥胖人群中代谢异常者年龄标化患病率分别为42.32%、60.31%和72.31%。在各体型人群中,男性代谢异常患病率均高于女性(P<0.01);代谢异常患病率均随年龄增长呈上升趋势(P<0.01)。不同地区体重正常和肥胖人群代谢异常患病率差异有统计学意义(P<0.01),东北地区代谢异常患病率最高,西南地区最低。不同表型者的年龄、体格指标及血清生化指标比较,差异均有统计学意义(P<0.01)。结论在中国人群中代谢正常肥胖(MNO)流行率较低,而超过40%的体重正常者伴有代谢异常。
Objective To understand the metabolic abnormalities in different body types. Methods According to the exclusion criteria, 7 849 people were screened from the data of 10 241 Chinese health and nutrition survey databases in 2009, and the data of socio-demographic, anthropometric and serum biochemical indexes were collected. According to the level of BMI were divided into normal weight group, overweight group and obesity group, according to the metabolic state is divided into normal metabolic group and abnormal metabolic group, combined with body shape and metabolic group of 6 phenotypes, compared different body types of metabolic abnormalities prevalence and Different phenotypes of body and serum biochemical differences. Results Of the 7 849 people who were included in the analysis, 2 554 (32.54%) and 822 (10.47%) were overweight and obese, respectively, and the metabolic abnormalities were 5 091 (64.86%). The age-standardized prevalence rates of normal and overweight and obese individuals with metabolic abnormalities were 42.32%, 60.31% and 72.31%, respectively. The prevalence of abnormal metabolic rate was higher in males than in females (P <0.01). The prevalence of metabolic abnormalities increased with age (P <0.01). The prevalence of metabolic abnormalities in normal weight and obese people in different areas was significantly different (P <0.01). The prevalence of metabolic abnormalities in northeast China was the highest and lowest in southwest China. There were significant differences in age, physical index and serum biochemical indexes between different phenotypes (P <0.01). Conclusions The prevalence of MNO in Chinese population is low, while more than 40% of normal weight patients have metabolic abnormalities.