目的　探讨结肠脂肪瘤的临床特点。方法　对 6例结肠脂肪瘤患者的资料进行回顾性分析。结果　结肠脂肪瘤主要表现为腹痛、腹部肿块、粘液血便及并发肠梗阻 ;纤维结肠镜、钡灌肠、消化道钡餐、CT等检查是结肠脂肪瘤诊断的重要手段。治疗以手术为主。结论　结肠脂肪瘤发病率低 ,无特殊临床表现 ,诊断困难 ,术前确诊率低 ,误诊率高。 Objective To investigate the clinical features of colonic lipoma. Methods Six patients with colonic lipoma were retrospectively analyzed. Results Colonic lipoma mainly manifested as abdominal pain, abdominal mass, mucoid bloody stool and intestinal obstruction; colonoscopy, barium enema, gastrointestinal barium meal, CT examination is an important means of diagnosis of colonic lipoma. The main treatment is surgery. Conclusion The incidence of colonic lipoma is low, no special clinical manifestations, diagnosis difficult, low preoperative diagnosis, misdiagnosis rate.