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目的：探讨心肌缺血和急性心肌梗死（AMI）对心血管自主神经活动的影响。方法：用24小时动态心电图检测心肌缺血组34例，AMI组22例，对照组32名健康人的心率变异性（HRV）指标。结果：五项HRV昼夜指标中，正常人除全程相邻正常窦性心搏间期之差的均方根值RMSSD这一指标外，其余四项均有显著性差异（P ＜0．05,P ＜0．01），但心肌缺血组和AMI组的昼夜HRV指标无显著性差异，而且，这两组的夜间全部正常窦性心搏间期的标准差（SDNN）比日间大，对照组则相反。结论：心肌缺血和AMI可致交感神经和迷走神经平衡失调；AMI对心血管自主神经的损害较心肌缺血更为严重。
Objective: To investigate the effects of myocardial ischemia and acute myocardial infarction (AMI) on cardiovascular autonomic nervous system activity. Methods: Heart rate variability (HRV) was measured in 24 patients with myocardial ischemia, 24 patients with AMI, 22 patients with AMI, and 32 healthy controls. Results: Among the five HRV circadian indexes, the other four had significant differences (P <0.05, P <0.05) except the mean square root of the difference between adjacent normal sinus beats P <0.01). However, there was no significant difference between daytime and nighttime HRV indexes in myocardial ischemia group and AMI group. Moreover, the standard deviation (SDNN) The opposite. Conclusion: Myocardial ischemia and AMI can cause imbalance of sympathetic and vagal nerves. AMI can damage cardiovascular autonomic nerve more than myocardial ischemia.