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目的了解河南省15岁以下儿童急性弛缓性麻痹病例(Acute Flaccid Paralysis,AFP)流行病学特征,为其防控策略制定提供科学依据。方法对2004-2012年河南省急性弛缓性麻痹病例监测系统报告5 247例15岁以下AFP病例进行描述性分析。结果河南省15岁以下儿童AFP病例主要表现为散发,年平均发病率为2.92/10万,其中郑州、安阳和济源发病率居前三位,分别为4.55/10万、4.48/10万和4.19/10万。发病高峰多出现于每年8-10月和3月,0~4岁组发病率较高。男性发病率高于女性,男女性别比为2.16∶1。891例AFP病例分离出肠道病毒,肠道病毒分离率为16.98%。15.04%的病例麻痹60 d有残留麻痹。结论河南省15岁以下儿童AFP病例以小年龄组为主,发病高峰多出现于夏秋季、春季,男性发病率高于女性,儿童AFP病例残留麻痹率较高,应及时采取措施降低致残率。
Objective To understand the epidemiological characteristics of Acute Flaccid Paralysis (AFP) in children under 15 years of age in Henan Province, and to provide a scientific basis for their prevention and control strategies. Methods Descriptive analysis of 5,247 AFP cases under 15 years of age was conducted in Henan Acute Flaccid Paralysis Surveillance System from 2004 to 2012. Results AFP cases of children under 15 years old in Henan province were mainly distributed with the annual average incidence of 2.92 per 100 000. Among them, the incidence of AFP in Zhengzhou, Anyang and Jiyuan ranked the top three with 4.55 / 100000, 4.48 / 100000 and 4.19 /100,000. Incidence peak appeared more in August-October and March each year, 0 to 4-year-old group had a higher incidence. The incidence of males was higher than that of females, and the ratio of male to female was 2.16: 1.891 cases of enterovirus isolated from AFP cases. The rate of enterovirus isolation was 16.98%. 15.04% cases of paralysis 60d residual paralysis. Conclusions AFP cases in children under 15 years of age in Henan Province are mainly in the younger age group. The peak incidence appears mostly in summer and autumn. In spring, the incidence of AFP in children is higher than that in females. The residual paralysis rate of children with AFP is high. Measures should be taken in time to reduce the morbidity .