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目的探讨儿童食物过敏与相关消化系统疾病的特点。方法本次研究选择的对象共40例,均为我院2010年2月至2012年2月收治的由食物过敏诱导发生的消化系统疾病,对其临床资料进行分析。结果本组共40例患儿中,慢性腹泻症状10例,占25%;慢性腹痛症状19例,占47.5%;肠易激综合征1例,占2.5%;厌食症状4例,占10%;反复呕吐症状6例,占15%。共有39例患儿检出特异性IgG(14种食物过敏原),为97.5%检出率。特异性IgG呈升高表现的1种食物过敏原5例,2种12例,3种12例,4～9种共10例。鸡蛋为37例,占最高比重;其次为牛奶29例,小麦16例,大豆11例,猪肉和鸡肉均为0。经随访后发现,本组总有效率为90%,无其他异常情况发生。鸡蛋检出率显著高于其他食物种类,差异有显著统计学意义(P<0.05)。结论对儿童特异性IgG食物过敏原进行测定,可提高相关消化系统疾病的确诊率,便于及时对饮食进行调整,有效改善临床症状,提高患儿生存质量。
Objective To investigate the characteristics of children with food allergy and related digestive diseases. Methods A total of 40 subjects selected in this study were all digestive diseases induced by food allergy in our hospital from February 2010 to February 2012 and their clinical data were analyzed. Results A total of 40 cases of children with chronic diarrhea in 10 cases, accounting for 25%; chronic abdominal pain in 19 cases, accounting for 47.5%; irritable bowel syndrome in 1 case, accounting for 2.5%; anorexia symptoms in 4 cases, accounting for 10% ; Recurrent vomiting in 6 cases, accounting for 15%. A total of 39 children were detected specific IgG (14 food allergens), was 97.5% detection rate. Specific IgG showed increased performance of a food allergens in 5 cases, 2 in 12 cases, 3 in 12 cases, 4 to 9 in 10 cases. Egg 37 cases, accounting for the highest proportion; followed by milk 29 cases, 16 cases of wheat, soybean 11 cases, pork and chicken are 0. After follow-up found that the total effective rate was 90%, no other abnormalities occurred. The detection rate of egg was significantly higher than other kinds of food, the difference was statistically significant (P <0.05). Conclusion The determination of children ’s specific IgG food allergens can improve the diagnosis rate of related digestive diseases, facilitate the timely adjustment of diet, effectively improve clinical symptoms and improve children’ s quality of life.