为阐明毫米波对胚胎产生损伤效应阈值及导致学习记忆功能降低的机理，明确毫米波的生物效应有无频率特异性，用６０ＧＨｚ、功率密度１～８ｍＷ·ｃｍ２的毫米波，在小鼠怀孕６～１５ｄ时进行２ｈ·ｄ１辐射。用电迷宫对子鼠进行学习记忆功能测试，分别用ＲＢＡ、ＨＰＬＣ－ＥＣＤ、ＲＩＡ法对子鼠脑Ｍ－胆碱能受体（Ｍ－Ｒ）、单胺递质和精氨酸加压素（ＡＶＰ）进行测定。结果如下，≥３ｍＷ·ｃｍ２的辐射导致成年子鼠学习记忆功能明显降低、成年子鼠海马区Ｂｍａｘ明显升高、足孕胚胎及成年子鼠脑中多巴胺（ＤＡ）含量明显降低，８ｍＷ·ｃｍ２辐射导致成年子鼠下丘脑及垂体中ＡＶＰ含量明显降低。结论为：６０ＧＨｚ毫米波辐射导致胚胎损伤的阈值在１～３ｍＷ·ｃｍ２，其导致子鼠学习记忆功能降低与使子鼠脑中ＡＶＰ、ＤＡ含量下降及海马区胆碱能神经活性降低相关，未见毫米波频率特异性效应 In order to elucidate the threshold effect of millimeter wave on embryos and the mechanism of reducing the learning and memory function, the biological effects of millimeter wave were determined whether there was frequency specificity or not by using millimeter wave of 60GHz and power density of 1 ~ 8mW · cm2 in mice Pregnancy 6 ~ 15d 2h d 1 radiation. Using electric maze, the learning and memory function of the offspring was tested. The effects of M-R, monoamine neurotransmitter and arginine vasopressin on RBA, HPLC-ECD and RIA (AVP). The results are as follows, radiation ≥ 3mW · cm 2 caused significantly reduced learning and memory in adult mice, Bmax in hippocampus of adult rats significantly increased, foot embryonic and adult offspring of brain dopamine (DA) decreased significantly, 8mW · cm  2 radiation caused adult hypothalamus and pituitary AVP levels were significantly lower. The conclusion is that the threshold of embryo damage caused by 60GHz millimeter wave radiation is 1 ~ 3mW · cm2, which leads to the decrease of learning and memory abilities in offspring rats and the decrease of AVP and DA contents in brain and the decrease of cholinergic activity in hippocampus , No millimeter-wave frequency-specific effects